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Plasmapheresis (plasma exchange)

plasmapheresis · plasma exchange · blood cleansing · plasma filtration

A machine draws your blood, separates the liquid part, called plasma, and returns the blood cells to you. This removes harmful substances from the blood.

For some diseases of the immune system, blood and nervous system, and for poisoning, as decided by the doctor.

⏱ Duration: a session usually takes 1 to 3 hours; a course is several sessions

Be sure to tell your doctor

How to prepare

  • Food. Usually a light breakfast before the session. Check with the clinic.
  • Medicines. Do not stop them on your own. The timing may change, and the doctor will tell you.
  • Clothing. Loose clothes with a wide sleeve.

What to bring

  • Your referral
  • Your ID
  • A list of your medicines
  • Water and a book

How it goes

  1. You are weighed and your blood pressure is taken
  2. A catheter is placed in a vein, or connected if you already have one
  3. Blood goes into the machine and the plasma is separated
  4. Blood cells are returned with a replacement fluid
  5. The nurse watches your blood pressure and how you feel
  6. At the end the system is disconnected

What you'll feel

  • A needle prick when the catheter is placed
  • Cold, or tingling of the lips or fingers: tell the nurse
  • Sometimes weakness and dizziness

Afterwards

  • Sit for a while before you stand up
  • Take it easy for the rest of the day
  • Drink water unless the doctor limited it
  • Come to the next sessions on schedule

Contact a doctor straight away if

  • Rash, itching, swelling of the face or trouble breathing: call your local emergency number
  • Severe dizziness or fainting
  • Bleeding or swelling at the catheter site
  • Fever or chills

Common questions

Does plasmapheresis "clean the body" for everyone?

No. It is a medical procedure for specific conditions, and a doctor prescribes it.

How many sessions will I need?

It depends on the illness. Usually a course of several sessions.