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Antinuclear antibodies (ANA)

ANA test · antinuclear antibodies · ANA screen · autoimmune blood test

This is a blood test from a vein. It looks for antibodies that the immune system sometimes makes against your own cells.

For a possible autoimmune disease: joint pain, a rash, or a long-lasting fever with no clear cause.

⏱ Duration: the blood draw takes a few minutes; results usually come in a few days, sometimes up to a week

Be sure to tell your doctor

How to prepare

  • Food. Best in the morning before eating, or a few hours after a light meal. Check with the lab.
  • The day before. For 24 hours, no alcohol and no hard workouts. Best not to smoke in the morning.
  • Medicines. Do not stop them on your own. Tell your doctor what you take. They will decide if anything should change.

What to bring

  • Your test request form
  • Your ID
  • Past test results, if you have them

How it goes

  1. You sit down and rest your arm on the armrest
  2. A band is tightened above your elbow
  3. The skin is wiped with antiseptic
  4. A quick prick, and blood fills a tube
  5. The needle comes out, and a cotton pad is pressed on the spot

What you'll feel

  • A quick prick, like a pinch
  • Sometimes slight dizziness. Tell the nurse

Afterwards

  • Press the cotton pad for 3 to 5 minutes and keep your arm straight
  • You can eat right away and go back to your usual day
  • The result is often given as a titer and a pattern. Your doctor will explain it
  • Results usually come in a few days. The lab will tell you when

Common questions

Does a positive ANA mean I have a disease?

No. A low titer can be found in healthy people. Your symptoms and other tests matter.